By A H Rebar; et al
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Additional resources for A Guide to Hematology in Dogs and Cats
They are thus more likely to notice and diagnose rare and unusual abnormalities. ® Identification of bizarre or neoplastic cells is a job for an expert; unusual or highly abnormal samples should be sent to a laboratory with a board-certified veterinary clinical pathologist. ® Red cell parasites and inclusions can also be difficult to differentiate and should be sent for expert confirmation. 27 TNM GuideToHema:03058 TNM text_cp 6/28/07 3:49 PM Page 28 ® Commercial laboratories can provide additional commentary on unusual findings and consultation with veterinary clinical pathologists.
Organisms must be differentiated from stain precipitate (Figure 4-20) and Cytauxzoon felis (Figure 4-32). ® Feline haemobartonellosis can occur as a primary disease or secondary to other immunosuppressive disorders such as FeLV infection, FIV infection, or FIP infection. ® Primary haemobartonellosis presents as a typical regenerative hemolytic anemia. Organisms appear intermittently in large numbers on peripheral erythrocytes. 51 TNM GuideToHema:03058 TNM text_cp 6/28/07 3:49 PM Page 52 ® Secondary haemobartonellosis often presents as a severe nonregenerative anemia.
Refractile artifact. Air bubbles trapped in the area of central pallor produces a refractile rounded structure that may be confused with an RBC inclusion. These structures “jewel” as the fine focus is moved and can be seen in a plane of focus that is beyond the RBC membrane (100x). ® Stain precipitate must also be differentiated from basophilic stippling (Figure 4-22). Over-staining of red cells ® Slides which have been exposed to formalin fumes will have an overall greenish discoloration when stained.